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Among them, omics technologies reveal multidimensional molecular insights into disease mechanisms, AI allows intelligent enhancement of diagnostic and therapeutic workflows, and personalized nursing provide comprehensive management systems centered around the patient

After consideration of public comments, we are finalizing as proposed the code descriptor for HCPCS code G0557: HCPCS code G0557 ( Advanced primary care management services for a patient with multiple (two or more) chronic conditions expected to last at least 12 months, or until the death of the patient, which place the patient at significant risk of death, acute exacerbation/decompensation, or functional decline, provided by clinical staff and directed by a physician or other qualified health care professional who is responsible for all primary care and serves as the continuing focal point for all needed health care services, per calendar month, with the following elements, as appropriate: Consent

Based on this concept, we trained a bagged ensemble of least absolute shrinkage and selection operator (LASSO) aging models for 11 major organs using the mutually exclusive organ-enriched proteins we identified as inputs (Fig