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The result of this embodiment shows that ACOT7 directly or indirectly participates in the metabolism of Q10 potentially.Therefore, targeting ACOT7 can promote the adjusting of the interior level of cell of Q10, thereby influences the effect of cell Q10

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Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity