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Given the substantial behavioral variability characteristic of ASD, insufficient sample sizes represent an important source of bias in preclinical studies

Across these conditions, LC3-to-lysosome flux was not significantly altered by changes in GABARAPL2 S10 phosphorylation, indicating that S10D does not measurably impair inducible bulk autophagy flux

Although dietary calcium restriction was previously thought to lower urine calcium and calcium-containing stone risk, evidence from multiple large observational studies and a randomized controlled trial has shown that calcium restriction does not prevent stone formation (Friedlander 2015)