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Visible changes in brightness and evenness of skin tone may take several weeks to months, depending on baseline pigmentation, dose, route of administration, and adherence to sun protection. Results are often subtle and natural-looking, and ongoing maintenance may be required to sustain benefits, especially in individuals with high sun exposure

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In addition, it was found that BPC 157 effectively reduced some of the symptoms occurring in the serotonin syndrome [26], thus exhibiting a rather specific counteraction of an excessive stimulation of 5-HT receptor subtypes (5-HT2A rather than 5-HT1A)

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