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Both direct and indirect pathways can penetrate the bloodbrain barrier (BBB), as illustrated in Figure 2

For healthcare providers, understanding its effectiveness and safety profile is essential for ensuring quality patient care

Regarding the possible mechanism of carcinogenesis, low levels of Cr(VI) exposure from drinking water may trigger the formation of high ROS levels, which in turn may help to induce the formation of tumors due to DNA mutations, increasing cell proliferation, altering the epigenome, preventing cell death, and accelerating tumor growth (Shin et al

Sample-level quality control also included visual inspection of quality control plots, hierarchical clustering, and principal component analysis (PCA) to identify potential outliers