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The overall mean change from baseline after VitE supplementation showed an increase in the serum VitE level, (MD = 1.04 mg/dL, 95% CI [0.131.94], P = .03)

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In particular, exogenous estrogens, be they oral contraceptives, estrogen patches or with estrogen replacement therapy are strong contributors to an underlying porphyria deficit [13, 14]

Nowadays, SPS has been a common strategy in synthetic chemistry labs due to its advantages, since through a single filtration of resin-bound chemicals it allows to quickly and simply separate the desired products from the by-products and intermediates existing in the reaction mixture 180