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In Mtb, pharmacological inhibition of PyrG could interfere with DNA/RNA biosynthesis, and other nucleotide-dependent metabolic processes, such as the biosynthesis of fatty acids, carbohydrates, amino acids, and cAMP or c-di-AMP [295]

Injections were considered

It acts directly on neighboring -cells to inhibit the secretion of glucagon and can also indirectly influence -cells by inhibiting the secretion of other hormones