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Description

Astragaloside-IV alleviates high glucose-induced ferroptosis in retinal pigment epithelial cells by disrupting the expression of miR-138-5p/Sirt1/Nrf2

Microb Cell Fact (2015) 14:137

IVR connects the BTB domain with the Kelch/DGR domain

This highlights an important conceptual point: ferroptosis sensitivity is determined not only by GSH abundance but also by the metabolic capacity to sustain reductive flux under oxidative stress