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Severe symptoms and reactions can occur, and working with a professional can help a person avoid or manage these symptoms

A subset was re-evaluated at 6 months (n=47), 1 year (n=26) and 2-9 years (n=33) after LT

Prodrugs: Challenges and Rewards Vol

To overcome this limitation, research efforts have been devoted to the development of therapeutic agents with biological mechanisms of action that are independent of the oxygen concentration