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Oxidative stress can affect the expression and activity of HDAC2 protein in a variety of ways, resulting in hormone resistance (46), which may adversely affect the treatment of asthma

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In a recent randomized, placebo-controlled trial in 50 subjects with recent onset of schizophrenia who were medicated, daily supplementation with EPA (740 mg) and DHA (400 mg) reduced psychotic symptoms (assessed with the Brief Psychiatric Rating Scale) only in those who were not taking the anxiolytic, lorazepam (Ativan) (200)