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Application of Bioassay-Guided Fractionation Coupled with a Molecular Approach for the Dereplication of Antimicrobial Metabolites

This was associated with the activation of mitochondrial unfolded protein response (UPRmt) signaling and modulation of mitochondrial proteostasis, which can ameliorate misfolded protein accumulation

doi: 10.1016/j.cbi.2017.12.024 35

Methods: We used the National Readmission Database (2016-2020) which includes discharges for patients with and without repeat hospital visits in a year and those who have died in the hospital