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Description

Metabolism The biotransformation of ARISTADA INITIO likely involves enzyme-mediated hydrolysis to form N-hydroxymethyl-aripiprazole, which subsequently undergoes hydrolysis to aripiprazole

It is also often used to create liposomes , small spheres surrounded by phospholipid bi-layer designed to carry some active ingredient and help its absorption

Patients with p.I278T mutations may exhibit variable responses to B6, whereas those with p.R125Q or p.R266K mutation variants require different therapeutic approaches (25,40,81)