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doi:10.1371/journal.ppat.1006286 23

Resuscitation-promoting factors as lytic enzymes for bacterial growth and signaling

HJM-561 exhibits potent degradation of EGFR Del19/T790M/C797S ( DC : 9.2 nM) and L858R/T790M/C797S ( 50 DC : 5.8 nM), and has anti-tumor activity (pink: EGFR ligand (HY-12857)