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Nonalcoholic steatohepatitis as the progressive disease entity often leads to fibrosis and end-stage disease

Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults

Regarding reproductive hormones, testicular I/R injury significantly decreased serum FSH and LH levels, whereas testosterone levels remained unchanged compared to the SH group

The human gene encodes for two isoforms of the enzyme, namely PEMT1, which is localized in the endoplasmic reticulum and generating most of the PEMT activity, and PEMT2, a liver specific isoform exclusively localized in mitochondriaassociated membranes (Tessitore et al., 2003)