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However, hyperactivation of PPAR by TZD may induce adipose tissue expansion, weight gain and fatty liver in patients and animals 1,2,3 and adipogenesis in vitro 4,5

Progress in Neuro - Psychopharmacology and Biological Psychiatry (2015)

An Afe I restriction site directly upstream of the Strep -tag II, together with the unique Xba I restriction site in front of the whole reading frame, was subsequently used to exchange the entire coding region for sfGFP by the ones for different other POIs (see Supplementary Table S1)