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JNMA J Nepal Med Assoc

Despite the fact that some tumours initially demonstrate impressive responses to chemotherapy or targeted agents, achieving a minimal residual disease (MRD) state, the majority of tumours eventually recur often without known resistance mutations

In addition, the AHR signaling pathway genes had a good predictive efficacy in missed abortion

For example, the anaerobic respiration of cells increases under anoxic conditions, which leads to the accumulation of lactic acid and forms an acidic environment, which is not conducive to the function of cytotoxic T lymphocytes (CTL) and reduces the toxicity of natural killer cells (NK cells) (130, 131)