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The effects of cannabidiol on nitric oxide synthases: a narrative review on therapeutic implications for inflammation and oxidative stress in health and disease Journal of Cannabis Research Springer Nature Link Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation resolving lipid mediators: Cell Chemical Biology The Neurotherapeutic Arsenal in Cannabis sativa: Insights into Anti Neuroinflammatory and Neuroprotective Activity and Potential Entourage Effects PMC Molecular and Cellular Mechanisms of Action of Cannabidiol PMC

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doi: 10.1038/s41573-022-00571-8 54 JiangLKonNLiTWangSJSuTHibshooshHet al

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typhimurium activates caspase-1/4/11-GSDMD inflammasome pathway, while acetaminophen toxicity begins with its metabolic conversion to reactive chemical species, N-acetyl-p-benzoquinoneimine (NAPQI), which causes hepatocyte necrosis 47