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The PPAR agonists rosiglitazone and pioglitazone were recently found to reduce the levels of 2-HG and H3K4me3 in the colon of mice with colitis and to regulate GSH and ROS levels in lamina propria lymphocytes by modulating GLS1/2-HG/H3K4me3 signaling in mouse models of colitis and asthma ( Table 1 )

This powerful antioxidant also provides additional wellness benefits, such as detoxification and immune support

Extracted proteins were quantified using a Pierce BCA Protein Assay kit (Thermo Scientific, 23225)

[DOI] [PMC free article] [PubMed] [Google Scholar] Salgado N., Silva M.A., Figueira M.E., Costa H.S., Albuquerque T.G