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Finally, gene ontology (GO) analysis indicated a significant enrichment of DEGs in the NLR family pyrin domain containing 1 ( NLRP1 ), absent in melanoma 2 ( AIM2 ), and NLR family pyrin domain containing 3 ( NLRP3 ) inflammasome complexes, and NADPH oxidase complex within the cellular component (GO-cellular component), a significant enrichment of DEGs in the inflammatory response and inflammation-related pathways within the biological process component (GO-biological process), and an enrichment of DEGs in the toll-like receptor 4 binding, arachidonic acid binding, and 2-alkenal reductase [NAD(P)] activity within the molecular function component (GO-molecular function) (Fig

The activation of estrogen receptor leads to increased expression of cyclins, and prompts cancer cells to transition from the quiescent phase to the proliferative phase 31 , leading to tumor growth and development

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