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Science 337 , 13401343 (2012)

Recent advances in the repair of degenerative intervertebral disc for preclinical applications

Altered Methylation: Preserved SAM for other methylation reactions 5

DNA methylation refers to the transfer of the methyl group provided by SAM to the 5-position carbon atom of cytosine, catalyzed by methyltransferase (DNMT), to form 5-methylcytosine