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A deficiency in B12 can lead to nerve damage, potentially impairing the signals between the brain and the penis that are necessary for erections

doi: 10.2337/diabetes.54.6.1615 10 GabbayKH

It also has a distinctive regulatory position: it was previously an FDA-approved product (marketed as Geref, a diagnostic agent) before being voluntarily withdrawn from the market, and that prior-approval history has given it a more stable standing for compounding than most other peptides