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doi: 10.1038/s41467-023-43458-x 22 GulatiGSDSilvaJPLiuYWangLNewmanAM

159 Although the mechanism by which cGAS-STING axis activates NLRP3 inflammasome remains unclear, these findings provide new evidence that mtDNA-mediated DAMPs can also mediate inflammasome activation via the cGAS-STING-NLRP3 axis

These compounds target many of the pathways associated with biological aging

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