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This activates protein kinase A, which then activates hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids that can be burned for energy

labs looks like this: Normal range: 200 to 900 pg/mL (some labs use 160 to 950 pg/mL) Optimal range: 400 to 600 pg/mL Elevated: above 900 to 1,000 pg/mL (hypercobalaminemia) These ranges come from sources including UCSF Health and WebMD, though your labs specific cutoffs may differ

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Metabolic findings in rodents have a long history of not translating cleanly, so the fat-loss story should be read as promising preclinical data, not an established human outcome