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Grill E, Lffler S, Winnacker EL, Zenk MH (1989) Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific -glutamylcysteine dipeptidyl transpeptidase (phytochelatin synthase)

In light of this scenario, personalized medicine emerges as a promising strategy to counteract the deleterious effects of aging on biological rhythmicity and to enhance therapeutic responses in elderly patients