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Description

Glutathione reductase (GR), a dimeric flavoprotein, is encoded by the GSR gene and is found in various tissues

Mol Neurodegener 13:43

Molecules 26(11):3143 Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, Herr R, Brabletz S, Stemmler MP, Brabletz T (2016) ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

We speculate that the latter is related to a decrease in IGF-1 bioactivity in the absence of neuromuscular activity, due to alterations in receptor density, binding protein, or postreceptor events