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Arm pain is common following the administration of meningococcal vaccines, as the Centers for Disease Control and Prevention (CDC) confirms

This is particularly relevant in PD where sustained microglial activation in inflammasome signaling intensifies oxidative stress, disrupts synaptic integrity and accelerates dopaminergic cell loss

Other combinations of entero-pancreatic hormones including cagrisema (GLP-1/amylin RA) and the triple agonist retatrutide (GLP-1/GIP/glucagon RA) have also progressed to phase 3 trials as obesity treatments and early data suggests that may lead to even greater WL than tirzepatide

Aroda VR, Edelstein SL, Goldberg RB, et al