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Clin Toxicol (Phila) 47:8188

While Turner et al.s primary results suggested that resveratrol has potential in slowing functional decline, other clinical assessments, including the Clinical Dementia Rating-Sum of Boxes, ADAS-cog, MMSE, and Neuropsychiatric Inventory do not reflect this effect [77]

Although in the normal adult human brain the level of 3R-tau is similar to that of 4R-tau, immunocytochemistry and biochemical analysis indicate that the ratio of 3R- to 4R-tau is altered in AD and other neurodegenerative disorders (191)