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Beyond direct H 2 O 2 scavenging, GSH also detoxifies lipid peroxidation byproducts, including malondialdehyde (MDA) and 4-HNE, through GST-mediated conjugation, facilitating their removal and preventing secondary cytotoxic signaling 91,92

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Morbidity and mortality after lifestyle intervention for people with impaired glucose tolerance: 30-year results of the Da Qing Diabetes Prevention Outcome Study