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Oral administration of SCFAs to germ-free -synuclein mice promoted neuroinflammation and motor dysfunction, and FMT with Parkinsons disease-affected patients enhanced the Parkinsonism compared to FMT from healthy human donors

Roboz G, Pabst T, Aribi A, Brandwein J, Dhner H, Fiedler W, Gandini D, Geddes M, Hou J, Howes A, Hultberg A, Huselton E, Jacobs J, Kane C, Lech-Marada E, Louwers M, Nottage K, Platzbecker U, Rampal R, Salman M, Shah P, Stevens D, Stuart M, Subklewe M, Sumbul A, Wang E, Wierzbowska A, Yao B, Yee, K, Kantarjian H, Borthakur G

This adjustment is to offset the challenges associated with adoption of eCQMs because of the organizational complexity required by definition of virtual groups and APM Entities and is therefore not appropriate for other types of participants or collection types such as MIPS CQMs or Medicare CQMs

At the end of establishment phase, evaluate your results against your documented starting condition