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1 Introduction Osteoarthritis (OA) is one of the most common forms of arthritis, affecting over 500 million people worldwide, and damage to articular cartilage is one of the most prevalent pathological changes in OA ( Articular cartilage is an avascular, aneural, and alymphatic tissue ( However, the role of immune cells in cartilage damage during OA remains controversial in existing research, with debates over whether they act as foes or friends

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Somatosensory projections to cochlear nucleus are upregulated after unilateral deafness