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For instance, patients with chronic intestinal inflammatory diseases, such as inflammatory bowel disease (IBD), often exhibit impaired intestinal barrier function and increased mucosal permeability, which facilitates bacterial translocation (137)

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Nei modelli murini di ictus e lesioni cerebrali, il peptide ha dimostrato di prevenire lapoptosi neuronale agendo sul pathway miR-339-5p / VEGFA , migliorando le funzioni cognitive e motorie

The pan-PPAR agonist lanifibranor decreased hepatic lipid accumulation, liver enzyme levels, and biomarkers of inflammation in plasma and improved fibrosis in an IIb clinical trial