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The primary responsibility of the MT1 receptor involves regulating the circadian cycle, while MT2 receptors control the body temperature through the peripheral tissue

Amyotrophic Lateral Sclerosis (ALS) is a devastating multisystem neurodegenerative disease characterized by the degeneration of both upper (cortical) and lower (brainstem and spinal) motor neurons, leading to progressive voluntary muscle weakness and paralysis

Similar to that in the Gpx4 flox/flox Vav-Cre mice, the HSPC phenotype was not impaired in the Gpx4 flox/flox Mx-Cre mice treated with pIpC (Supplementary Fig