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2 As new ideas for analgesic drug design are urgently needed, the biological processes responsible for chronic pain have been the focus of preclinical research to identify potential targets for drug discovery

59 However, their application in cardiovascular disease has raised important safety concerns

Los hepatocitos son las nicas clulas que tienen la habilidad de utilizar metionina para la sntesis de GSH a travs de la va de la transulfuracin, en la cual la metionina es convertida a cistena y luego esta ltima es utilizada en la sntesis de GSH (6)(26)