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Cancer Chemother Pharmacol 77:659662 Rodrigues D, de Souza T, Coyle L, Di Piazza M, Herpers B, Ferreira S, de Kok TM (2021) New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids

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Root Cause Remains Unaddressed A critical limitation of current treatment approaches is that they do not correct the underlying defect in hemoglobin production

Monocytes and Macrophages D2-like DRs participate in a cAMP-independent pathway to regulate macrophage phagocytic function, thus reducing the secretion of IL-2, IL-4, and IFN- (104), the effect of which is concentration-dependent