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Essays in Biochemistry, Vol 42: The Biochemical Basis of the Health Effects of Exercise

Although the same effects have not yet been verified in humans, a study in mice showed that extreme restriction of both carbohydrates and protein should be avoided because of potential development of fatty liver Non-alcoholic-Fatty Liver-Disease (NAFLD) or even worse, progression of the fatty liver to actual liver damage as is seen in Non-alcoholic Steatohepatitis (NASH)