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Hormone-related observations provide a hypothesis for research, not evidence of therapeutic effectiveness

AAPS PharmSciTech 4 , 3644 (2003) Castro, G.T., Filippa, M.A., Sancho, M.I., Gasull, E.I., Almandoz, M.C.: Solvent effect on the solubility and absorption spectra of meloxicam: experimental and theoretical calculations

Se deficiency can cause several diseases and even cause reproductive disorders in humans and animals [77]

This leads to an imbalance in the glutathione/reactive oxygen species (ROS) axis and enhanced pyrimidine biosynthesis, which in turn sustains the cancer stem cell-like properties of lung cancer cells and drives the malignant progression of NSCLC ( Metabolites involved in the serine/glycine pathway are markedly depleted in the plasma of NSCLC patients after radiotherapy and in corresponding cellular models, indicating that tumor cells utilize these metabolites to facilitate DNA damage repair and cell survival