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195,196 Future research should elucidate the roles of SIRT1 in the microbiotaimmunemetabolism cross-pathways and evaluate its potential therapeutic synergy with microbiota-targeted interventions, including probiotics and dietary fibers

doi: 10.1002/glia.20967 133 OngrD.DrevetsW

These immunological alterations which have characterized our current understanding of Covid-19 suggest that agents which target immune modulation, rather than direct viricidal activity, may present exciting targets for pharmacological intervention