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These transcriptomic signatures can help to identify disease stages and progression and represent a potential alternative to liver biopsy for diagnosis and monitoring

It is evident that the overexpression of multiple proteins can saturate the cells capacity to properly fold proteins, and expressing the additional PDIs will compensate for defects in disulphide formation and isomerization, resulting in an enhanced capacity of the engineered yeast cells for GSH production

This ensures optimal absorption without interference from food or digestive processes

It acts as the "welder" that fuses the amino acid chains together