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Description

Serotonin is synthesized in a two-step pathway that utilizes the coenzyme tetrahydrobiopterin (BH4) in and pyridoxal phosphate (PLP)

10.1016/j.btre.2019.e00370 81 KurutasE

Archived from the original on 29 April 2020

Polyphenol metabolites with neurotransmitter function can cross BBB or also exert influence through the cerebrovascular system, such as curcumin and its derivatives that act against nitrosative stress and mitochondrial malfunction [226]