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and (3) enhanced therapeutic benefits were observed in patients with higher BMI or Metabolic dysfunctionrelated chronic conditions disease

Zhao et al (39) also observed a decrease in inner mitochondrial membrane and ER damage in zebrafish retinal cells treated with copper sulfate

Furthermore, BHB influences adipocytes by upregulating uncoupling protein 1 (UCP1) and PR domain containing 16 (PRDM16) via the AMP-activated protein kinase(AMPK)/SIRT1/PGC-1 pathway, resulting in reductions in body weight and lipid levels [112]