glutathione liver disease Dysregulation of synthesis in Glutathione-mediated biotransformation in the liver

Fasano, a world-renowned gastroenterologist, in order for autoimmunity to be triggered, three factors must be present (this is referred to as the three-legged stool of autoimmunity): [1] A genetic predisposition Intestinal permeability/leaky gut A triggering event or root cause factor Each of these three legs or factors plays its own role in triggering autoimmunity (explained throughout this article)

Li Zhou from Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences

*Correspondence: Bonglee Kim, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Kalinina, E