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However, supraphysiologic concentrations achieved in clinical trials of BPM31510 are associated with reliable and consistent safety and tolerability profiles (NCT02650804, NCT03020602, NCT01957735), supporting non-deleterious effects in normal cells compared to cancer

Acknowledgements This work was supported by the BK21 FOUR (Fostering Outstanding Universities for Research) and the Basic Science Research Program through the National Research Foundation of Korea (NRF), by the Ministry of Science and ICT (MSIT) (2022R1A2C1004204), and by the Soonchunhyang University Research Fund

Experimental challenge models for johnes disease: A review and proposed international guidelines

MORE Type 1 diabetes mellitus (T1DM), also known as insulin-dependent diabetes, is a chronic disease caused by autoimmune (type 1a) or spontaneous (type 1b) destruction of pancreatic beta cells, resulting in insulin deficiency