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Whitening and anti-aging agent 3

The results indicate that the Fe content across these nanozymes is relatively consistent, with the HCFe nanozyme displaying a Fe content of approximately 10.5026%, placing it in the median range among the tested nanozymes (Table S7)

The hydrogen peroxide contents in the tissues were measured based on protocol as previously described (Jiang et al., 1992

Mutation-specific therapies aim to correct the underlying mutation through the use of a gene-editing platform or replace the faulty mtDNA-encoded protein by delivering the wild-type gene using a suitable vector