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A vegan diet is generally healthy, low in cholesterol and protective of heart disease, but its followers must take vitamin B12 supplements or risk a condition that causes permanent numbness in their hands and feet, experts say

The popliteal vein ascends to become the femoral vein (in the adductor canal and femoral triangle), then joins the deep femoral vein to form the common femoral vein , which drains into the external iliac and common iliac veins , ultimately entering the inferior vena cava

With my own research (and this forum) I found out that that my three monthly B12 treatment was insufficient and was the cause of my megaloblastic anaemia

In a post hoc analysis after 13 years of the study, a 13% increased risk of vitamin B12 deficiency per year of metformin use was reported (Aroda et al, 2016)