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Blood 137 , 35913594 (2021)

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These effects are mainly achieved by the driving effect of NAD + on metabolic pathways as enzyme cofactors transferring hydrogen in oxidation-reduction reactions

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These serve as cytoplasmic antigens, whose cross-presentation is primarily mediated by specific DC subsets through adaptation of their endocytic and phagocytic pathways to initiate CD8+ T cell responses (82)

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