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The available human data from published literature and ongoing pregnancy registry studies on use of oxcarbazepine during pregnancy have not demonstrated an increased prevalence of major congenital malformations with first trimester exposure, though they acknowledge that the published studies do have limitations

Diabetes 60 , 4755 (2011)

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Under the joint regulation of existing mitochondrial nuclear DNA (nDNA) and mitochondrial DNA (mtDNA), new mitochondria are synthesized to replace damaged mitochondria, so as to repair mitochondrial structure, maintain mitochondrial function, increase antioxidant effect, reduce pathological oxidative stress and promote ATP production to meet the metabolic needs of eukaryotic cells under physiological and pathological conditions (Popov, 2020