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Phytother Res, 20 (10), 859-64

[30] The extensivity of the -catenin interacting proteins complicates our understanding: -catenin may be directly phosphorylated at Ser552 by Akt, which causes its disassociation from cell-cell contacts and accumulation in cytosol, thereafter 14-3-3 interacts with -catenin (pSer552) and enhances its nuclear translocation

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For microneedling-style facial treatments, redness often improves within the first 24 to 48 hours, while swelling, bruising, or peeling can last a bit longer