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Cells were grown in RPMI 1640 medium containing 10 % fetal bovine serum (Hyclone, USA) in a 37C humidified incubator containing 5 % CO 2 and 95 % air

doi: 10.31557/APJCP.2021.22.4.991 61

Iron binds to the Nterminal metalbinding domain of syn, stabilizing its sheetrich conformation and accelerating the formation of oligomerization [211]

Although mTORi have been evaluated in combination with CNI in reducing the long-term risk of nephrotoxicity, studies on early transition to mTORi-based immunosuppressive regimens among liver transplant (LT) recipients are limited