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[1] [13] Deficiency [edit] Carnitine deficiency is rare in healthy people without metabolic disorders, indicating that most people have normal, adequate levels of carnitine normally produced through fatty acid metabolism

A recent study on mice demonstrated that maternal obesity induced sex-specific alterations in the repressive histone mark H3K9me3 in offspring livers, which were accompanied by marked malefemale differences in gene expression, particularly in metabolic and stress-response pathways [150]

doi:10.1097/hjh.0000000000001356 Hubbard GP, Wolffram S, de Vos R, Bovy A, Gibbins JM, Lovegrove JA

Eur J Pharmacol 923:174938 Thomas R, Srivastava S, Katreddy RR, Sobieski J, Weihua Z (2019) Kinase-inactivated EGFR is required for the survival of wild-type EGFR-expressing cancer cells treated with tyrosine kinase inhibitors