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The spliced version is translated, and the resulting protein translocates to the nucleus and induces expression of ER chaperones, secretory genes and genes encoding proteins of ER-associated degradation, which mediates transport of unfolded proteins to the proteasome for degradation [81, 82]

2012, doi:10.1186/1755-7682-5-2 Kim, Stephanie et al

Quinlan CL, Orr AL, Perevoshchikova IV, Treberg JR, Ackrell BA, Brand MD

116 Emerging Diagnostic Strategies Serum protein S100-beta is a novel diagnostic biomarker of neurological injury, and blood levels may be useful in distinguishing neurological origins from other possible causes